Make sure your laser cutter has a lid and the laser beam is completely enclosed. Lasers powerful enough to cut thru cardboard can damage eyesight. Much easier to close a lid than hope everyone in the area is wearing laser rated safety goggles.
Have a good venting system with a fan or blower. Someone is eventually going to cut something they shouldn’t or use the wrong settings. Having the laser vented to the outside or into a good filter box will keep minor errors minor.